A condition in which there is absence of a pair of chromosome 22 is known as Digeorge syndrome. Normally the child inherits equal pairs of chromosome from the mother and father and each chromosome contains roughly 500-800 genes. In Digeorge syndrome, the child will have only one copy of the chromosome 22 and misses the other copy. This deleted chromosome can be from his father or mother during the development of fetus and is reflected in all cells of the baby.
Some of the symptoms of Digeorge syndrome are weakness, poor muscular structure, and bluish skin, improper circulation of blood, poor weight gain, and shortness of breath, getting infection frequently, difficulty in feeding and delayed development of the child. For some children, there may be a gap in the cleft palate and retarded speech. In some cases, there may be wide eyes with narrow groove in the upper lip region.