Aicardi syndrome is a rare disorder affecting girls. The exact cause for this disorder is not known but it is genetic disorder. Newborn girls with this problem will develop seizures during 1-3 months or before completing first year. In this disorder the connection between the two hemispheres of the brain is disturbed in the region of corpus collusum. Treatment of Aicardi syndrome is given only for managing the symptoms of seizures and developmental delay.
Causes :
Aicardi syndrome is caused by gene mutation but this disorder is not passed on to the offspring by the parent. Gene mutation is involved in the X chromosomes of the girls causing complete absence of corpus collusum that connects two hemispheres of the brain. It would produce complex form of seizures starting during infancy. It may cause retinal lacunae marking lesions on the retina of the child.
It was JD Aicardi, a French doctor who found this syndrome in his study conducted with children with partial closure of corpus collusum and vision abnormalities. Aicardi syndrome is a rare disorder and can cause mental retardation in the affected children. It can cause sudden death and very rarely affected children will enter into adolescence.