Initial symptoms can be detected in the fetus and also after birth. These children would have under-developed bones, drooping eyelids, lateral eyebrows with long distance between the eyes. They might also have some behavioral problems and they are often shy and stubborn in character. The growth of multiple organs can be affected. Such children have low birth weight and short attention span. Having eye abnormalities are quite common in children with this disorder.
Causes :
Dubowitz syndrome is genetic and caused by autosomal recessive pattern of genes inherited by birth. Both the parents should have mutated genes in them to pass it on to their child. Parents with one child having this syndrome have increased chance to have their next child also affected. Dubowitz syndrome is a rare disorder in which children are born with defective genes affecting normal growth.